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KMID : 0604520060320040249
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Journal of the Society of Cosmetic Scientists of Korea
2006 Volume.32 No. 4 p.249 ~ p.255
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Application as a Cosmeceutical Ingredient of Methanolic Extract from Ardisia crenata
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Lee Dae-Woo
Kim Young-Jin
Kim Young-Sil
Eom Sang-Yong
Kim Jong-Heon
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Abstract
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In this study, we evaluated anti-oxidation, whitening and anti-inflammatory effects of Ardisia crenata for use as the cosmeceuticals. Ardisia crenata extract (70% MeOH) showed a significant free-radical scavenging effect (up to 90% over at the concentration of 0.01 %) against DPPH radical generation and showed a significant inhibitory effect (up to 50% over at the concentration of 0.05 %) on melanin synthesis in B16 meanoma cells. We separated 5 fractions from Ardisia crenata extract (70% MeOH) by MPLC. The 3rd, 4th, and 5th fractions showed the anti-oxidation (DPPH radical scavenging activity and supressive effect on Mn-SOD), whitening (inhibitory effect on melanin synthesis) and anti-inflammatory (supressive effects on IL-1{alpha}, IL-6, COX-2 and total NO synthesis) effects.
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KEYWORD
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Ardisia crenata, anti-oxidation, melanogenesis, anti-inflammation, IL-1{\alpha}
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